First Lady

Harriet Lane

Vice President

John C. Breckinridge (1857–1861)

Secretary of State

Lewis Cass (1857–1860)

Secretary of State

Jeremiah S. Black (1860–1861)

Secretary of the Interior

Jacob Thompson (1857–1861)

Attorney General

Jeremiah S. Black (1857–1860)

Attorney General

Edwin M. Stanton (1860–1861)

Postmaster General

Horatio King (1861)

Postmaster General

Aaron V. Brown (1857–1859)

Postmaster General

Joseph Holt (1859–1861)

Secretary of the Treasury

Howell Cobb (1857–1860)

Secretary of the Treasury

Philip F. Thomas (1860–1861)

Secretary of the Treasury

John A. Dix (1861)

Secretary of the Navy

Isaac Toucey (1857–1861)

Secretary of War

John B. Floyd (1857–1860)

Secretary of War

Joseph Holt (1861)