First Lady

Abigail Fillmore

Vice President

none

Secretary of State

Edward Everett (1852–1853)

Secretary of State

Daniel Webster (1850–1852)

Secretary of State

John M. Clayton (1850)

Secretary of the Interior

Alexander H. H. Stuart (1850–1853)

Secretary of the Interior

Thomas M. T. McKennan (1850)

Attorney General

John J. Crittenden (1850–1853)

Attorney General

Reverdy Johnson (1850)

Postmaster General

Samuel D. Hubbard (1852–1853)

Postmaster General

Nathan K. Hall (1850–1852)

Postmaster General

Jacob Collamer (1850)

Secretary of the Treasury

Thomas Corwin (1850–1853)

Secretary of the Treasury

William M. Meredith (1850)

Secretary of the Treasury

Thomas Ewing (1850)

Secretary of the Navy

John P. Kennedy (1852–1853)

Secretary of the Navy

William A. Graham (1850–1852)

Secretary of the Navy

William B. Preston (1850)

Secretary of War

Charles M. Conrad (1850–1853)

Secretary of War

George W. Crawford (1850)